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PROMAMA® Maternal Milk for Pregnant and Lactating Mothers

Nutrition during pregnancy has a significant impact on physical and mental development 1


The period between the third trimester to two years of age is vital for brain development 7


Nutrition plays an important role in the critical developmental stage of the brain and consequently in the function and maintenance of the brain. 8, 9

Therefore, it is important to know that Choline, helps to support your child’s cognitive development and other key nutrients such as Choline, DHA, Folic Acid, Vitamin B12, Iron and Iodine helps support your child’s cognitive development 6, 10-13.

Is Constipation common during pregnancy?

Constipation is common during pregnancy, occuring in 11-38% OF PREGNANT WOMAN 16 and EVEN IN LACTATING WOMEN 17,18


In order to support optimal maternal health and foetal development, it is essential for pregnant mothers to have a gastrointestinal system that is capable of digesting nutrients in an optimal intestinal environment

• OLIGOFRUCTOSE is a soluble dietary fiber that has been shown to increase the BENEFICIAL BIFIDOBACTERIA in the gut flora 14

• Studies have shown that fiber supplements INCREASED STOOL FREQUENCY and IMPROVED STOOL CONSISTENCY 5,14,15



  • 1. Lammi-Keefe CJ, Couch SC, Philipson EH. Handbook of nutrition and pregnancy. 2008. Humana Press.
  • 2. European Food Safety Authority Panel on Dietetic Products, Nutrition and Allergies (ND); Scientific opinion on the substantiation of health claims realted to folate and blood formation (ID 79), homocysteine metabolism (ID 80), energy-yielding metabolism (ID 90), function of the immune system (ID 91), function of blood vessels (ID 94, 175, 192), cell division (ID 193), and maternal tissue growth during pregnancy (ID 2882) pursuant to Article 13 (1) of Regulation (EC) No 1924/2006. On request from European Commision. EFSA Journal 2009; 7 (9): 1213. [22 p.p]. doi:10.2903/j.efsa.2009.1213. Available online: www.efsa.europa.eu.
  • 3. Food and Agricultural Organization of the United Nations. Human vitamins and minerals requriments: report of a joint FAO/World Health Organization expert consultation. 2nd edition, 2004. http://www.who.int/iris/handle/10665/42716/1/9241546123.pdf. EFSA 2010.
  • 4. Hanson MA, Bardsley A, De-Regil LM et. Al. The International Federation of Gynecology and Obstetrics (FIGO) recommendations on adolescent, preconception, and maternal nutrition. “Think Nutrition First”. Int J Gynecolo Obstet. 2015 Oct; 131 Suppl 4:5213-53.
  • 5. MRC. Vitamin Study Research Group. Prevention of neural tube defects: Results of the Medical Research Council Vitamin Study. Lancet 1991;338: 131-37 (S-26® MAMA Medical Justification 2013).
  • 6. Prado EL, Dewey KG. Nutrition and brain development in early life. Nutr Rev. 2014; 72 (4): 267-284.
  • 7. Lauritzen L. Hansen HS, JØrgensen MH, Michaelsen KF. The essentiality of long chain n-3 fatty acids in relation to development and function of the brain and retina. Prog Lipid Res. 2001;40(1-2):1-94.
  • 8. Altshuler K, Berg M, Frazier LM, Laurenson J, Longstreth J, Mendez W, Molgaard CM. Critical Periods in Development: OCHP Paper Series on Children's Health and the Environment. Paper 2003-2, U.S. Environmental Protection Agency. 2003;1–48.
  • 9. Tau GZ, Peterson BS. Normal Development of Brain Circuits. Neuropsychopharmacology. 2010; 35(1):147–168.
  • 10.Wu BTF, Dyer RA, King DJ, Richardson KJ, Innis SM. Early second trimester maternal plasma choline and betaine are related to measures of early cognitive development in term infants. PLoS ONE 7(8):e43448.doi:10.1371/journaLpone.0043448. 2012.
  • 11. Surtees R, Leonard J, Austin S. Association of demyelination with deficiency of cerebrospinal-fluid 5-adenosylmethionine in inborn errors of methyl-transfer pathway. Lancet.1991;338:1550-1554.
  • 12. Martinez M, Mougan I. Fatty acid composition of human brain phospholipids during normal development. J Neurochem. 1998;71(6):2528-2533.
  • 13. Don AS, Hsiao JH, Bleasel JM, Couttas TA, Halliday GM, Kim WS. Altered lipid levels provide evidence for myelin dysfunction in multiple system atrophy. Acta Neuropathol Commun. 2014;2:150.
  • 14. Roberfroid M, Gibson GR, Hoyles L et al. Pre biotic effects: metabolic and health benefits. Br J Nutr. 2010 Aug; 104(suppl 2):S1-63
  • 15. Rungsiprakarn P, Laopaiboon M, Sangkomkamhang US. et. al. Interventions for treating constipation in pregnancy. Cochrane Database Syst. Rev. 2015;9: CD011448.
  • 16. Koletzko B, Boey CCM, Campoy C et al. Current information and Asian perspective on long chain polyunsatured fatty acids in pregnancy, lactation and infancy: systematic review and practice recommendations from an early nutrition academy workshop. Ann Nutr. Metab 2014; 65: 49-80.
  • 17. Jewell D, Young G. Interventions for treating constipation in pregnancy (Review). The Cochrane Library 2012, Issue 2.
  • 18. Bradley CS, Kennedy CM, Turcea AM et al. Constipation in pregnancy – prevelance, sympotoms, and risk factors. Obstet Gynaecol. 2007;110:1351-1357.

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